In this large multi center prospective study of patients presenting to the ED with acute chest pain, the use of high sensitivity cardiac troponin T on arrival and at 1 hour resulted in a sensitivity of 100% for “rule outs” and specificity of 97% for “rule ins”. Based on the algorithm (based on troponin values and delta from arrival to 1 hour), 77% of patients could be ruled in or ruled out in 1 hour. This easy to use algorithm can quickly rule in or out over 3/4 of ED patients with acute chest pain (abstract)
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