By  | August 31, 2012 |  0
In this large randomized trial of patients with a recent lacunar infarct, the addition of clopidogrel to ASA did not reduce the risk of recurrent stroke, but the risk of major bleeding was twice as high (2% vs 1% per year). There is no benefit, and there is harm, when clopidogrel is added to ASA […]
By  | August 31, 2012 |  0
In this large trial of patients with stable CAD, those with a fractional flow reserve (FFR) of <80% (which indicates functionally significant stenosis), they were randomized to medical therapy or PCI; PCI had a significantly lower rate of death/MI/urgent revascularization compared to medical therapy (4% vs 13%). In patients with stable CAD and FFR<80%, PCI […]
By  | August 31, 2012 |  0
In this large randomized trial (CREST trial) of patients with carotid stenosis who underwent either CEA or carotid stenting, the rate of restenosis at 2 years was ~6% in both groups, indicating both procedures are reasonable in short and long term outcomes (abstract)
By  | August 31, 2012 |  0
In this large cohort of anticoagulated Afib patients, HAS-BLED performed the best in predicting clinically relevant bleeding, compared to HEMORR2HAGES or ATRIA, with receiver-operating characteristic (ROC) scores of 0.60, 0.55, and 0.50 respectively. HAS-BLED is the best to date risk score for predicting bleeding in anticoagulated Afib patients (abstract)
By  | August 31, 2012 |  0
Based on consensus from the American College of Cardiology, American Heart Association, European Society of Cardiology, and World Heart Federation has now defined AMI as a cardiac troponin (I or T) level > 99th%, and 1+ of the following (abstract): ischemia symptoms new ST/T wave changes or LBBB new pathologic Q waves new nonviable myocardium or […]
By  | August 31, 2012 |  0
In this Cochrane meta-analysis of 7 trials, IVIg was as effective as plasma exchange in reducing disability scores, with no significant difference in adverse events (abstract)