In this large analysis of all Cdiff cases in Olmsted County, Minnesota from 1991 to 2005, 41% of all cases were community acquired. Compared to hospital acquired, they were more likely to occur in younger healthier women without exposure to antibiotics (22% had no history of antibiotics. There were not significant differences in community or hospital acquired with respect to severity or recurrence rates. Hospitalists should be aware of the frequency of community acquired Cdiff, 22% of which have not been exposed to antibiotics (abstract)
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]