In this large trial of patients with severe traumatic brain injury, they were randomized to placebo or amantadine for 4 weeks, and followed for functional recovery. The rate of functional recovery was significantly better for the amantadine group, with no difference between the groups in adverse events. Amantadine should be standard therapy for patients post severe traumatic brain injury (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.