Several scoring systems exist to help identify which patients are at higher risk of death in non-variceal UGI bleeds. This 10-point scoring system, the PNED, was prospectively validated on 1360 patients, and outperformed the Rockall, with AUCs of 0.81 and 0.66, respectively. This scoring system appears to predict mortality as well if not better than the commonly utilized Rockall score, and is another option to risk stratify patients with non-variceal UGI bleeds (abstract)
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]