In this trial of 310 patients aged 55-70, they were randomized to bioprosthetic or mechanical aortic valve replacement. There were no significant differences between the groups in peri-operative or long-term mortality, thromboembolism, bleeding, endocarditis, or major adverse prosthetic related events. The bioprosthetic group had higher rates of valve failure/re-operations (2.3% vs 0.6% per patient year), but the mechanical group had non-significantly higher rates of bleeding. The type of aortic valve choice depends on which risk is more tolerable: re-operation or bleeding (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.