In this meta-analysis of 8 randomized trials involving 1726 patients, BNP-guided CHF management reduced overall mortality (compared to usual care), but did not reduce hospitalizations. Those in the BNP guided groups were more likely to achieve target doses of beta blockers and ACE inhibitors (which is likely causally related to the reduction in mortality). BNP guided CHF management may have role in the outpatient setting to get patients to target doses of medications, but does not reduce hospitalization rates (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.