In this large trial of 4733 diabetics with hypertension on 3 drugs, they were randomized to intensive (SBP <120 mmHg) or standard (SBP <140 mmHg) blood pressure control. It took a mean of 3.4 versus 2.1 medications to get to goal in the 2 groups. The 5 year risk of adverse cardiovascular events was equivalent between the 2 groups, but the intensive group had significantly more serious adverse events. High risk diabetics should not be targeted for intensive BP lowering (<120 mmHg) (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.