In this meta-analysis of randomized controlled trials of CRT in patients with any degree of symptoms and EF<40%, CRT was beneficial in patients in with Class I-II CHF symptoms, with lower all cause mortality and CHF hospitalizations, but no improvement in functional status or quality of life. There is evidence that CRT improved outcomes in patients not only with CHF Class III-IV, but also with Class I-II. However, CRT is associated with the risks of infection (1.4%) leasd problems (6.2%) mechanical complications (3.2%) and procedure-related deaths (0.3%) (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.