In this large retrospective analysis from 2 tertiary care academic medical centers, 7% of patients were exposed to >4 grams/day of acetaminophen; of those >age 65 or with chronic liver disease, 18% exceeded the recommended dose of 3 grams/day. Hospitalists need to be mindful of acetaminophen dosing in hospitalized patients, especially those with chronic liver disease or > age 65 (abstract).
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]