In this randomized trial of patients with acute stroke s/p t-PA, they were randomized to further endovascular treatment or no treatment; the trial was stopped early, as the 90 day Rankin and NIHSS scores were no different between the groups, nor was mortality. Currently, the use of endovascular treatment after t-PA has unproven benefit (abstract).
The AHA/ASA has updated their guidelines for the management of acute stroke; they stress the need for early thrombolytics, early transfer to a stroke center or use of telemedicine consultation when feasible. The full guidelines are at (AHA/ASA)
This large meta-analysis of 52 trials found that SSRIs significantly reduced the risk of neurological deficit, dependence, disability, depression, and anxiety post stroke, compared to controls (abstract).
In this analysis from 2000-2009 from the Get with the Guidelines registry of patients with in-hospital cardiac arrest, 80% had asystole or PEA, and 20% Vfib/Vtach. Survival to discharge increased from 14% to 22% over the time period. Neurological disability also decreased from 33% to 28% over the time period. Advances in in-hospital arrest have improved survival and reduced neurological disability rates (abstract).
The American Academy of Neurology (AAN) has issued updated guidelines on the treatment of Bell's palsy; they concluded that steroids are "probably effective" and antivirals are "possibly effective". The steroids should be continued for 10 days, and best outcomes were noted in those started within 3 days of onset (guidelines)