The ACC/AHA/ACG has issued a consensus statement on the use of GI prophylaxis (primarily PPIs) in patients on anti-platelet agents (primarily ASA and clopidogrel). The summary states that patients at low risk for GI bleeding do not require GI prophylaxis. Risk factors that would require consideration of GI prophylaxis include: multiple agents (anticoagulants, NSAIDs, steroids), advanced age, history of GI bleeding, and HPylori infection. A full copy can be found at (site)
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