In this multicenter trial of intubated patients on sedation protocols, they were randomized to daily sedation interruption, or no additional intervention. There were no difference between the groups in time to successful intervention, ICU LOS, hospital LOS, delirium rates, or rates of unintentional extubation. The daily interruption group was associated with higher daily doses of opiates and benzodiazepines, and higher nursing workload. Daily sedation interruption, when added to sedation protocols, and no better than sedation protocols alone (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.