In this case-control study of dialysis and non-dialysis patients with UGI bleeding, all had endoscopic control of their bleeding, and received 3 days of IV PPI (40mg IV BID), then oral PPI (20mg qday) for 2 months. The rate of re-bleeding at 7 days was about the same in the 2 groups, but between 7-30 days, the dialysis group had significantly higher rates of re-bleeding (10% vs 0%). Higher PPI doses in dialysis patients at discharge may be necessary to reduce the intermediate risk of re-bleeding (abstract).
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.