Dronedarone is an amiodarone analogue (with fewer adverse side effects than amiodarone), which has been shown to reduce atrial fibrillation recurrence compared to placebo, but long term safety had not been established. In this large RCT of >4000 patients, patients on dronedarone had lower cardiac hospitalizations and death than those on placebo (after mean f/u of 21 months). There was no difference in the groups in pulmonary, liver, or thyroid toxicity, so this drug will likely replace some amiodarone in the management of patients with atrial fibrillation (abstract).
What comes to mind when you think of getting CME? I bet most of you would say sitting in an auditorium, whether that be during your local grand rounds or at our professional society meeting, like Hospital Medicine 16 in sunny San Diego this past March. Hanging out in the Twitterverse? Probably not so much… […]
As a nurse practitioner in hospital medicine I have multiple opportunities to interact with all sorts of physician hospitalist colleagues, hospital medicine group leaders, quality officers etc. Often their interactions with me take on a certain wary curiosity, like I am some exotic monkey or another creature that is unfamiliar to them. If I am […]
By reading the headlines recently, practitioners would not know if they saved or tanked the healthcare system. One day disaster looms, the next we have moderated growth and business can continue as usual (and by business, I mean doing the correct things correctly). A new study, along with some recent data, helps shed some light […]