Timing of cholecystectomy in patients with gallstone pancreatitis remains controversial. In this small trial, 50 patients with mild pancreatitis (Ranson score 3 or less) were randomized to early cholecystectomy (within 48 hours) or late cholecystectomy (after resolution of pain and improvement in labs). Those in the early group had significantly shorter LOS (mean 3.5 vs 5.8 days) with no difference need for open procedure or peri-operative complications. Early cholecystectomy in patients with mild gallstone pancreatitis may shorten hospital LOS without increasing complications (abstract)
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]