Hypomagnesemia with PPIs

The FDA has issued a warning on the risk of hypomagnesemia with long term PPI use. The proposed mechanism is reduced Mg absorption after long term use. The clinical significance and incidence is not yet known, but some patients in the report did not respond to Mg supplementation and had to be discontinued off their PPI (FDA site)

Danielle Scheurer

Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.

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