Kayexalate dose response in reducing K levels

In this retrospective single center cohort, patients with hyperkalemia (K>5.1) treated with sodium polystyrene (kayexalate) were examined to determine the dose given, and subsequent reduction in serum K. They found a dose response, with K level decreases ranging from 0.8 to 1.4 in those given 15g and 60g respectively. Serum potassium normalized after 1 dose in 94% of patients. Kayexalate dose should be given based on the required reduction in serum K (abstract)

Danielle Scheurer

Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.

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