In this retrospective single center cohort, patients with hyperkalemia (K>5.1) treated with sodium polystyrene (kayexalate) were examined to determine the dose given, and subsequent reduction in serum K. They found a dose response, with K level decreases ranging from 0.8 to 1.4 in those given 15g and 60g respectively. Serum potassium normalized after 1 dose in 94% of patients. Kayexalate dose should be given based on the required reduction in serum K (abstract)
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