Lack of significant benefit to GI prophylaxis in non-ICU patients

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By  |  February 14, 2011 | 

In this large retrospective propensity-matched cohort of patients hospitalized in a non-ICU setting for a LOS of at least 3 days, the risk of GI bleeding was significantly, but modestly, lower in those that received GI prophylaxis (adjusted odds ratio 0.63, CI 0.42 to 0.93). However, the number needed to treat to prevent 1 bleed was 770 (based on a prevalence of GI bleeding of 0.3%). Routine use of GI prophylaxis in non-critically ill patients should continue to be discouraged (abstract)

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About the Author: Danielle Scheurer

Danielle Scheurer, MD, MSCR, SFHM is a clinical hospitalist and the Chief Quality Officer at the Medical University of South Carolina in Charleston, South Carolina, where she also serves as Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She is also the President of SHM's Board of Directors and previously served as Physician Editor of The Hospitalist, SHM's monthly newsmagazine.

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