More doubt on tight ICU glucose control

In the highly anticipated NICE-SUGAR trial, over 6000 med-surg ICU patients from 42 hospitals were randomized to tight (81-108) or conventional (<180) glucose control. The primary outcome (90 day death) occurred in 28% of the tight, versus 25% of the conventional group, and severe hypoglycemia (<40) occurred in 7% versus <1%. Tight glucose control in adult ICU patients may be harmful, and goals should be liberalized to keep glucose 140-180 (time-weighted mean in the conventional group was 142) (abstract)

Danielle Scheurer

Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.

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