A new international consensus guideline has been published on the management of non-variceal upper GI bleeding (guidelines). Among the highlights, the guidelines stress the use of prognostic staging and early endoscopy. Post endoscopy, low risk patients should be candidates for early discharge, while high risk patients should be observed for re-bleeding on high-dose IV PPIs for 72 hours. ASA should be restarted within 7 days for those who require it (and ASA+PPI is preferred over clopidogrel). For those requiring NSAIDs, a PPI with a COX-2 inhibitor is preferred. In peptic ulcers, test (and treat) for Hpylori
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