Non-invasive ventilation after extubation

In trial of 106 patients with respiratory failure, immediately post-extubation they were randomized to non-invasive ventilation (for 24 hours) or conventional oxygen. Those in the non-invasive ventilation group were less likely to have respiratory failure at 72 hours (15% vs 48%), and had lower 90 day mortality (11% vs 31%) (where most of the causes of death were due to respiratory failure). A 24 hour trial of non-invasive ventilation post-extubation may reduce respiratory failure and mortality (abstract).

Danielle Scheurer

Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.

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