In this large retrospective cohort of elderly (age>66) nursing home residents with cognitive impairment, the mean rate of PEG insertions was 7 per 100 hospital stays (range from 0-39 per 100 hospital stay). Hospital characteristics associated with higher insertion rates were larger, for-profit, and with higher ICU utilization. Both the high insertion rate and the variability are disturbing, as there is little evidence of benefit of PEG insertions in elderly demented nursing home patients (abstract)
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]