PPIs increase risk of SBP in hospitalized cirrhotics

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By  |  April 20, 2012 | 

In this case-control study from a single institution of patients hospitalized with cirrhosis, those that developed SBP were almost twice as likely to have received a PPI in the previous 7 days (71% versus 42%), and those who had not taken a PPI in the past 90 days had a 70% lower odds of developing SBP compared to those that had received a PPI within the last 7 days. Although retrospective, this study should cause us to pause and consider the risks of starting or maintaining PPI therapy in patients hospitalized with cirrhosis (abstract)

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About the Author: Danielle Scheurer

Danielle Scheurer, MD, MSCR, SFHM is a clinical hospitalist and the Chief Quality Officer at the Medical University of South Carolina in Charleston, South Carolina, where she also serves as Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She is also the President of SHM's Board of Directors and previously served as Physician Editor of The Hospitalist, SHM's monthly newsmagazine.

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