In this large retrospective cohort, researchers determined a risk prediction score for Cdiff that had good predictive discrimination (C index 0.88); many of the risk factors are already well known, and include: age, Cdiff “density”, previous 60 day admits, modified Acute Physiology Score, high-risk antibiotic days, low albumin, ICU admission, and receipt of laxatives, gastric acid suppressors, or antimotility drugs. If further validated, this risk score may be used clinically to predict risk, and determine which patients need additional preventive strategies layered on (abstract)
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