Prediction rule for adverse drug reactions in hospitalized elderly

>
By  |  July 15, 2010 | 

This large multi-center cohort derived and validated a model to predict the risk of an adverse drug reaction (ADR) among hospitalized patients > age 65. They found the strongest predictors were previous ADR and number of medications, followed by liver disease, renal disease, 4+ conditions, or heart failure. Those prescribed 5 or more drugs had about double the risk of an ADR, and those prescribed more than 8 drugs had about a 4 fold risk of an ADR. The overall AUC of the model was 0.70. Poly-pharmacy in hospitalized elderly patients substantially increases the risk of an ADR (abstract).

Share This Post

Leave A Comment

For security, use of Google's reCAPTCHA service is required which is subject to the Google Privacy Policy and Terms of Use.

About the Author: Danielle Scheurer

Danielle Scheurer, MD, MSCR, SFHM is a clinical hospitalist and the Chief Quality Officer at the Medical University of South Carolina in Charleston, South Carolina, where she also serves as Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She is also the President of SHM's Board of Directors and previously served as Physician Editor of The Hospitalist, SHM's monthly newsmagazine.

Categories

Related Posts

January 25, 2021 |  0
Never let a good salary signal go to waste. Here is a meta-assembly of hospitalist, as well as comparator specialties, of 2018-19 salary moves courtesy of Modern Healthcare. It is useful seeing the various estimates from the leading consultants, placement firms, and intelligentsia to get some bearings on the pay trends, Covid notwithstanding.
February 18, 2020 |  0
This is the time of year to sit back at night, in front of the fireplace, a cup of hot chocolate in hand, warming up after the coolness of the day. As I sip, I notice the marshmallows bobbing up and down and reflect on the impact those white confections have in medicine. Yes, marshmallows […]
September 24, 2019 |  0
Look up from your stack of journals lately? You will note DNA analysis has gotten awfully popular. Mom, dad, and the rest of the clan want in and the temptation to obtain the blueprint that makes you, you has an almost hypnotic-like draw. You are curious if what grandma told you—half of your “G, C, […]
Go to Top