In this large retrospective database analysis, increasing acid suppressive intensity (from none to H2 blockers, to daily PPIs, to more than daily PPIs) linearly increased the risk of nosocomial Cdiff infection (from 0.3%, 0.6%, 0.9%, and 1.4% respectively), with corresponding adjusted odds ratios of 1, 1.5, 1.7, and 2.4 respectively. Intensity of acid suppressive therapy linearly increases the risk of nosocomial Cdiff infection (abstract)
Share This Post
Categories
Related Posts
Do you have a stack of journals piling up on your desk, beside your bed or in your email inbox? In 1950, medical knowledge was estimated to double every 50 years, but now the doubling time is every few months. At this rate, it is impossible to keep up with the literature, but a group […]
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
Leave A Comment