In this large derivation and validation cohort, the HAS-BLED risk score helped predict the risk of bleeding in patients with Afib (which can help determine accuracy of anti-platelet or oral anticoagulation drug benefit). The acronym applies a point each for: HTN (<160mmHg), Abnormal liver or renal function (1 point each), Stroke history, Bleed history (or h/o anemia), Labile INR (<60% therapeutic), Elderly (>age 65), Drugs (anti-platelet or NSAIDs)/alcohol (>8/week). Those with a score of 0 had 1 bleed/100 patient years; those with a score of 5+ had 13 bleeds/100 patient years. Overall C-stat of 0.72. This easy to calculate score can help determine anticoagulation candidacy in patients with Afib (abstract)
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