In this single center study, researchers examined the prevalence of prolonged shedding of influenza virus in hospitalized patients (detected by culture and PCR). Of 147 patients, viral RNA was detectable 1 week after symptom onset in 26% of oseltamivir-treated patients, and 57% of untreated patients. Prolonged clearance was associated with co-morbidities and systemic steroids (for asthma or COPD). In these high risk patients, prolonged viral shedding should be expected (abstract).
by Deepak Asudani, MD, MPH, FHM Whether it is the prompt and expeditious international collaboration to develop an Ebola vaccine, or tardy but promising development of the first anti parasitic malarial vaccine or the fascinating technology utilizing synthetic DNA for vaccine development against MERS, these developments promise to highlight significant strides in vaccine development for […]
Economists describe preferences in two ways: revealed and stated. Say, for example, I asked you to implement a penalty program for your team with the goal of decreasing the number of occasions members did not clean their hands after a patient encounter. Because you know bad hands equal bad outcomes, you’re apt to offer up […]
by Eric Howell, MD, SFHM “Tell me what you know about antibiotics.” That’s the discussion I start with hospitalized patients all the time, right after they ask me to prescribe antibiotics for their simple cough, or other viral-like illness. And, from their perspective, asking for antibiotics makes sense. After all, antibiotics have been the physician’s […]