Side effects of varenicline

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By  |  December 9, 2011 | 

Medical therapies for smoking cessation are limited, and the cardiovascular risk of varenicline is unresolved. This new analysis also increases existing concerns for psychiatric side effects with varenicline from the FDAs adverse event reporting system. Of all smoking cessation therapies (e.g. varenicline, buproprion, or nicotine therapies) 90% of depression/suicidality episodes were associated with varenicline; compared to nicotine replacement, varenicline had 8 times the odds of depression/suicidality. Ongoing concerns of serious side effects may limit the use of varenicline among some smokers (abstract)

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About the Author: Danielle Scheurer

Danielle Scheurer, MD, MSCR, SFHM is a clinical hospitalist and the Chief Quality Officer at the Medical University of South Carolina in Charleston, South Carolina, where she also serves as Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She is also the President of SHM's Board of Directors and previously served as Physician Editor of The Hospitalist, SHM's monthly newsmagazine.

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