In HIV patients who present with an opportunistic infection (OI), it is unknown if there is an advantage to early initiation of HAART. In this trial of 282 patients with HIV and an OI, they were randomized to early HAART (within 14 days of OI treatment) or delayed HAART (started after OI treatment was completed). At 48 weeks, progression of AIDS or death was significantly lower in the early group (14% vs 24%). This adds to the mounting evidence of benefit of early HAART (abstract).
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.