Stool transplants have been successful in a few case series of patients with recurrent or refractory Cdiff. This case series describes self-administered (by enema) stool transplants (from family members) in 7 patients with refractory Cdiff. They report 100% clinical success with 14 months of follow up. The donor was extensively tested for infectious agents before donating the fecal specimen. Although cumbersome, this may be a feasible option in patients with ongoing Cdiff that is refractory to other treatments (abstract).
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.