In this large cohort of 4202 patients followed in an anticoagulation clinic for MI, atrial fibrillation, or mechanical heart valves, researchers determined untoward effects (major thromboembolism or major hemorrhage) occurred at a rate of 4% per year. The optimal intensity (fewest number of untoward events) for heart valves was an INR 2.5-2.9, for atrial fibrillation was 3-3.4, and for MI was 3.5-3.9 (abstract).
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.