In this double dummy trial of 170 patients admitted to the ICU with COPD/respiratory failure (without pneumonia), there were no differences in outcomes (death, need for additional antibiotics, length of stay, or ventilator days) between the 2 groups. This study and others confirms TMP-SMX works just as well as cipro for acute COPD exacerbations (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.