In this randomized trial of patients post cardiac surgery, they were randomized to transfusion triggers of HCT >30 or >24. The liberal group was transfused 78% of the time, and the restrictive group 47% of the time. There was no difference between the groups in the primary outcome (mortality or severe morbidity), but each transfused unit was an independent predictor of 30 day death or clinical complications (hazard ratio 1.2, CI 1.1-1.4, for each unit). A restrictive blood transfusion trigger for patients post cardiac surgery is non-inferior, and maybe superior, to a liberal trigger (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.