Patients with moderate to severe Cdiff are commonly treated with oral vancomycin, but there has been a theoretical concern of rectal VRE transmission from these patients. In this prospective observational study of patients with Cdiff and concurrent VRE colonization, researchers cultured skin and environmental samples from patients before, during, and after treatment with vancomycin or metronidazole. They found no difference in VRE-positive skin or environmental cultures between the 2 treatment groups, indicating VRE contamination from oral-vancomycin-treated patients should not be a substantial concern (abstract).
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]