In this diagnostic trial of 328 patients who underwent both capsule endoscopy and colonoscopy, capsule endoscopy had a sens/spec for polys of 64% and 84%, and sens/spec for advanced adenomas of 73% and 70%. The capsule “slept” through the small bowel, and “awoke” in the colon, but was significantly limited by the adequacy of the prep. Although less invasive that colonoscopy, capsule endoscopy currently suffers from similar limitations as CT colonography (diagnostic only and significantly limited by prep adequacy). Although intriguing, it is not quite ready for prime time (abstract).
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