In this diagnostic trial of 328 patients who underwent both capsule endoscopy and colonoscopy, capsule endoscopy had a sens/spec for polys of 64% and 84%, and sens/spec for advanced adenomas of 73% and 70%. The capsule “slept” through the small bowel, and “awoke” in the colon, but was significantly limited by the adequacy of the prep. Although less invasive that colonoscopy, capsule endoscopy currently suffers from similar limitations as CT colonography (diagnostic only and significantly limited by prep adequacy). Although intriguing, it is not quite ready for prime time (abstract).
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]