In this trial of patients with recurrent Cdiff, they were treated with vancomycin, then randomized to no further therapy, duodenal lavage, or duodenal infusion of donor feces. Those in the donor feces group had 81% resolution of disease at 10 weeks (after 1 infusion), compared to 23% of those in the lavage group, and 31% of the vancomycin only group, with no difference in adverse events. This will become the new standard of care for recurrent Cdiff (abstract).
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]