In this randomized trial of 144 patients with mild renal insufficiency (creatinine 1.1-2.0) undergoing elective cardiac catheterization, they were randomized to a single 20meq HCO3 bolus before contrast, and all received hydration. The incidence of nephropathy within 3 days (25% or 0.5 increase from baseline creatinine) was significantly lower in the HCO3 group (1% vs 13%). A single HCO3 bolus before contrast (added to hydration) appears to be effective in reducing post-procedure nephropathy in patients with mild renal insufficiency (abstract).
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September 20, 2009 |
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About the Author: Danielle Scheurer
Danielle Scheurer, MD, MSCR, SFHM is a clinical hospitalist and the Chief Quality Officer at the Medical University of South Carolina in Charleston, South Carolina, where she also serves as Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She is also the President of SHM's Board of Directors and previously served as Physician Editor of The Hospitalist, SHM's monthly newsmagazine.
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