IV enoxaparin at least as effective, and just as safe as unfractionated heparin for patients undergoing PCI

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By  |  August 26, 2011 | 

In this industry-sponsored trial, patients with STEMI were randomized before PCI to get standard dosing unfractionated heparin or 0.5mg/kg of IV lovenox. There were no significant differences between the groups in the primary outcome (death, complication, procedure failure, or bleeding), but enoxaparin preformed better than heparin in the secondary outcome (death, recurrent ACS, urgent revasularization). Given the ease of administration and predictable dose-response, IV lovenox may be appealing for STEMI before PCI, although cost is higher (abstract)

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About the Author: Danielle Scheurer

Danielle Scheurer, MD, MSCR, SFHM is a clinical hospitalist and the Chief Quality Officer at the Medical University of South Carolina in Charleston, South Carolina, where she also serves as Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She is also the President of SHM's Board of Directors and previously served as Physician Editor of The Hospitalist, SHM's monthly newsmagazine.

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