LMWH vs stockings neutral on all-cause mortality and major bleeding

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By  |  December 29, 2011 | 

In this large randomized trial of high risk hospitalized patients (eg >age 40 with CHF, cancer, or infection with at least 1 other risk factor for VTE), all cause mortality and major bleeding were no different between those receiving LMWH (40 qday) versus graduated compression stockings. Although this study was not designed to evaluate rate of asymptomatic or symptomatic VTE, there was only 1 fatal PE in each group. The caveats are that this international population had lower risk of VTE than past US study populations (lower rate of a past history of VTE, lower BMI), but nonetheless, mortality and bleeding did not differ between LMWH and stockings in these population of hospitalized medical patients (abstract)

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About the Author: Danielle Scheurer

Danielle Scheurer, MD, MSCR, SFHM is a clinical hospitalist and the Chief Quality Officer at the Medical University of South Carolina in Charleston, South Carolina, where she also serves as Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She is also the President of SHM's Board of Directors and previously served as Physician Editor of The Hospitalist, SHM's monthly newsmagazine.

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