In this large prospective single center cohort, 1031 low risk patients with chest pain (no history of CAD, negative EKG and enzymes) underwent coronary CT. Of the 625 with a coronary calcium score of zero, <1% had an acute coronary syndrome during the index hospitalization or during follow up. This study suggests that low risk chest pain patients with no coronary calcium on CT can be discharged home (abstract)
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