Since publication of the NICE-SUGAR trial, this meta-analysis of 26 trials found no overall mortality benefit to tight glucose control in ICU patients. They did find a mortality benefit in the subset of surgical ICU patients (RR 0.63, CI 0.44-0.91). However, the overall risk of hypoglycemia (<40) was markedly higher in tight glucose control group (RR 6, CI 4.5-8.0). Outside of the surgical ICU, tight glucose control appears to do more harm than good (abstract).
Have you ever wondered if there’s a correlation between Gore-Tex® (Think: rain jacket material) and Social Media? No!? Well, I have… It turns out there may be more commonality between these topics than what one might imagine. You see, Bill Gore (the company’s founder and CEO) recognized a particular number in his manufacturing plants: 150. […]
I just heard. A colleague, a man of integrity and warmth, a hard-working physician with ideals, ethics and many valued contributions, has taken his own life. His perspectives may have differed from mine at times, but every interaction was infused with respect. He was a good man. Much has been written about the rate of […]
The question of appropriate ward garb is a problem for the ages. Compared to photo stills and films from the 1960s, the doctors of today appear like vagabonds. No ties, no lab coats, and scrub tops have become the norm for a number (a majority ?) of hospital-based docs—and even more so on the surgical […]