In this case-control study from a single institution of patients hospitalized with cirrhosis, those that developed SBP were almost twice as likely to have received a PPI in the previous 7 days (71% versus 42%), and those who had not taken a PPI in the past 90 days had a 70% lower odds of developing SBP compared to those that had received a PPI within the last 7 days. Although retrospective, this study should cause us to pause and consider the risks of starting or maintaining PPI therapy in patients hospitalized with cirrhosis (abstract)
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]