This large multi-center cohort derived and validated a model to predict the risk of an adverse drug reaction (ADR) among hospitalized patients > age 65. They found the strongest predictors were previous ADR and number of medications, followed by liver disease, renal disease, 4+ conditions, or heart failure. Those prescribed 5 or more drugs had about double the risk of an ADR, and those prescribed more than 8 drugs had about a 4 fold risk of an ADR. The overall AUC of the model was 0.70. Poly-pharmacy in hospitalized elderly patients substantially increases the risk of an ADR (abstract).
Have you ever wondered if there’s a correlation between Gore-Tex® (Think: rain jacket material) and Social Media? No!? Well, I have… It turns out there may be more commonality between these topics than what one might imagine. You see, Bill Gore (the company’s founder and CEO) recognized a particular number in his manufacturing plants: 150. […]
I just heard. A colleague, a man of integrity and warmth, a hard-working physician with ideals, ethics and many valued contributions, has taken his own life. His perspectives may have differed from mine at times, but every interaction was infused with respect. He was a good man. Much has been written about the rate of […]
The question of appropriate ward garb is a problem for the ages. Compared to photo stills and films from the 1960s, the doctors of today appear like vagabonds. No ties, no lab coats, and scrub tops have become the norm for a number (a majority ?) of hospital-based docs—and even more so on the surgical […]