Re-start ASA after GI bleed

By  |  December 1, 2009 | 

In this trial of 156 patients on low-dose ASA (80mg) who developed peptic-ulcer-related GI bleeding, they were randomized, after endoscopic control of the bleeding, to continue ASA or placebo. Recurrent GI bleeding at 30-days was significantly higher in the ASA group (10% vs 5%), but the ASA group had lower 8-week all-cause mortality (1% vs 13%). Although ASA cessation after peptic-ulcer bleeding is associated with lower 30-day bleeding risk, it is also associated with higher 8-week mortality (abstract). It may be beneficial to immediately re-start the ASA in some patients.

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About the Author: Danielle Scheurer

Danielle Scheurer
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.


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