Who gets early stent thrombosis?

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By  |  March 4, 2009 | 

In the ACUITY trial of over 3400 patients with ACS who underwent stent implantation, the 30 day rate of stent thrombosis was 1.4% (no different with bare metal or drug-eluting stents). The most significant co-morbid factors associated with early stent thrombosis were insulin requiring diabetes, renal insufficiency, and overall burden of atherosclerosis. Lack of pre-procedural, or inconsistent 30 day use of a thienopyridine (such as clopidogrel) was also, not surprisingly, a strong predictor.  Although all patients should be counseled as to the importance of post-stent thienopyridine use, the message has to be loud and clear in those with renal insufficiency, diabetes, and high atherosclerotic burden (abstract).

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About the Author: Danielle Scheurer

Danielle Scheurer, MD, MSCR, SFHM is a clinical hospitalist and the Chief Quality Officer at the Medical University of South Carolina in Charleston, South Carolina, where she also serves as Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She is also the President of SHM's Board of Directors and previously served as Physician Editor of The Hospitalist, SHM's monthly newsmagazine.

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