Blood cultures are part of the standard work-up of patients with febrile neutropenia, but it is not clear how often they affect treatment management. In this large cohort of 126 patients with febrile neutropenia who had 2520 blood cultures, 9% were positive (14% in patients without prior antibiotics and 7% in patients receiving antibiotics). Of these, 78% were gram-positive, 21% were gram-negative, and <1% were fungal. The antibiotics were modified after the results half the time, indicating that blood cultures do affect management in a small, but significant, number of patients with febrile neutropenia (abstract).
I am coming up on my two year anniversary. Not my wedding anniversary (soon to be 15 years – thanks Maia!), but two years since I joined the ranks of the patients. It was two years ago this week that my day was interrupted by a page from my internist saying, “I don’t know how […]
As you can see, no glamour shots for this month’s post. I knew it would come at some point, and my first hospitalization related to my CLL came in a big way in mid-July. Given my interest in global health, it was only fitting that I managed to get sick while out of the […]
This large multicenter trial randomized patients with acute VTE to apixaban (10mg BID for 1 week, followed by 5mg BID for 6 months) versus conventional therapy (lovenox-warfarin). The primary outcome was similar between groups (symptomatic VTE or death related to VTE), but major and minor bleeding occurred significantly less often with apixaban. Apixaban is a […]