Acetaminophen and CVA

Higher body temperature has been associated with poor functional outcomes in patients with CVA. This multicenter trial randomized CVA patients (temp 36-39 C) to paracetamol (1gram q4 for 3 days) or placebo within 12 hours. Although there was no overall difference in the primary outcome (improvement beyond expectation), subgroup analysis did show improvement in those with temp 37-39 C, and no difference in serious adverse events between the 2 groups. An editorialist agrees that this seemingly innocuous intervention is likely highly valuable in CVA patients with elevated body temperatures (abstract)

Danielle Scheurer

Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.

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