The FDA has recommended a boxed warning be placed on promethazine to avoid intra-vascular or subcutaneous administration, due to the risk of tissue gangrene. Recommended administration is intramuscular (FDA site)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.